Home » Graduate Program (2018-2022) » Publications » Project 8

FORGI: Fibroblast tumor ORGanoids Immune cell co-culture – a new model to understand membrane-mediated tumor microenvironment interactions

10 project-relevant publications [ICEPHA PI(s) and PhD student(s) in bold letters] 

  1. Becker L, Fischer F, Fleck JL, Harland N, Herkommer A, Stenzl A, Aicher WK, Schenke-Layland K, Marzi J. 2022. Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids. Int J Mol Sci 23:doi:10.3390/ijms23136956
  2. Becker L, Janssen N, Layland SL, Murdter TE, Nies AT, Schenke-Layland K, Marzi J. 2021. Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring. Cancers (Basel) 13:doi:10.3390/cancers13225682
  3. Brauch H, Schroth W, Murdter T, Schwab M. 2019. Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same. J Clin Oncol 37:1981-2. doi:10.1200/JCO.19.00507
  4. Dong M, Bopple K, Thiel J, Winkler B, Liang C, Schueler J, Davies EJ, Barry ST, Metsalu T, Murdter TE, Sauer G, Ott G, Schwab M, Aulitzky WE. 2023. Perfusion Air Culture of Precision-Cut Tumor Slices: An Ex Vivo System to Evaluate Individual Drug Response under Controlled Culture Conditions. Cells 12:doi:10.3390/cells12050807
  5. Euler L, Gillard N, Delahaut P, Pierret G, Murdter T, Schwab M, Dohmen G, Thomas A, Thevis M. 2022. Assessing human urinary clomiphene metabolites after consumption of eggs from clomiphene-treated laying hens using chromatographic-mass spectrometric approaches. Anal Chim Acta 1202:339661. doi:10.1016/j.aca.2022.339661
  6. Klotz-Noack K, Klinger B, Rivera M, Bublitz N, Uhlitz F, Riemer P, Luthen M, Sell T, Kasack K, Gastl B, Ispasanie SSS, Simon T, Janssen N, Schwab M, Zuber J, Horst D, Bluthgen N, Schafer R, Morkel M, Sers C. 2020. SFPQ Depletion Is Synthetically Lethal with BRAF(V600E) in Colorectal Cancer Cells. Cell Rep 32:108184. doi:10.1016/j.celrep.2020.108184
  7. Kroner P, Heinkele G, Kerb R, Igel S, Schwab M, Murdter TE. 2021. Stereoselective quantification of phase 1 and 2 metabolites of clomiphene in human plasma and urine. Talanta 221:121658. doi:10.1016/j.talanta.2020.121658
  8. Mohr CJ, Schroth W, Murdter TE, Gross D, Maier S, Stegen B, Dragoi A, Steudel FA, Stehling S, Hoppe R, Madden S, Ruth P, Huber SM, Brauch H, Lukowski R. 2022. Subunits of BK channels promote breast cancer development and modulate responses to endocrine treatment in preclinical models. Br J Pharmacol 179:2906-24. doi:10.1111/bph.15147
  9. Schroth W, Buttner FA, Kandabarau S, Hoppe R, Fritz P, Kumbrink J, Kirchner T, Brauer HA, Ren Y, Henderson D, Madden SF, Sauer G, Fehm T, Wallwiener D, Fasching PA, Murdter T, Schwab M, Brauch H, German T, Group AIC. 2020. Gene Expression Signatures of BRCAness and Tumor Inflammation Define Subgroups of Early-Stage Hormone Receptor-Positive Breast Cancer Patients. Clin Cancer Res 26:6523-34. doi:10.1158/1078-0432.CCR-20-1923
  10. Stohr D, Schmid JO, Beigl TB, Mack A, Maichl DS, Cao K, Budai B, Fullstone G, Kontermann RE, Murdter TE, Tait SWG, Hagenlocher C, Pollak N, Scheurich P, Rehm M. 2020. Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids. Cell Death Differ 27:3037-52. doi:10.1038/s41418-020-0559-3