Overview of the Projects
Project | PIs | Title |
---|---|---|
1.
| B. Moussian / A. Nies | The model of the fruit fly Drosophila melanogaster as a novel and highly innovative test system for human membrane transporters in anti-cancer drug development
|
2.
| Validation of xenosensing nuclear receptor PXR as a therapeutic target in cancer chemotherapy
| |
3. | R. Lukowski, P. Ruth / W. Schroth, H. Brauch | The role of potassium channels and their gene variants for hormone-dependent breast cancer progression and endocrine treatment outcome |
4.
| K. Schulze-Osthoff, F. Essmann / M. Schwab, R. Hoppe | Role of the pro-apoptotic BCL-2 protein BOK in breast cancer
|
5.
| Amyloid beta and its degrading enzyme neprilysin as targets for treatment of liver fibrosis and prevention of hepatocellular carcinoma
| |
6.
| Establishment of Stable lsotope-resolved in vivo Metabolomics as Test System to assess Membrane-associated Drug Targets in Cancer
| |
7.
| Intratumor heterogeneity of members of the monocarboxylate transporter (MCT/SLC16) and organic cation transporter (OCT/SLC22) family in clear cell renal cell carcinoma (ccRCC)
| |
8.
| K. Schenke-Layland, E.M. Brauchle / T. Mürdter, N. Janssen | FORGI: Fibroblast tumor ORGanoids Immune cell co-culture – a new model to understand membrane-mediated tumor microenvironment interactions
|
Z1
|
| ICEPHA mouse clinic
|
Z2
|
| Administrative and central tasks
|