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Judith Jeske

Doctoral project:

The role of pregnane X receptor-dependent lipid metabolism in the pathophysiology of non-alcoholic fatty liver disease and its complications

Further reading:

Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor. Jeske J, Bitter A, Thasler WE, Weiss TS, Schwab M, Burk O. Biochem Pharmacol. 2017 Jul 15;136:122-135. doi: 10.1016/j.bcp.2017.04.013.

Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor. Jeske J, Windshügel B, Thasler WE, Schwab M, Burk O. Arch Toxicol. 2017 Jun;91(6):2375-2390. doi: 10.1007/s00204-017-1948-3.