Overview of the Projects
Project | PIs | Title |
1 | Stefan & Burk | The role of pregnane X receptor-dependent lipid metabolism in the pathophysiology of non-alcoholic fatty liver disease and its complications |
2 | Hailfinger, Schulze-Osthoff & Schäffeler, Schwab | Regulation of the CD147-MCT lactate transporter complex by the novel protein SMIM11 in cancerogenesis |
3 | Huber, Zips & Winter, Thomas | The SDF-1/CXCR4 axis in glioblastoma as biomarker and potential therapeutic target for radiation therapy |
4 | Laufer & Nies | Identification of transporters for drug disposition of the novel MAPK14 inhibitor Skepinone-L and ist regioisomers in combination with multikinase inhibitor sorafenib in human hepatocellular carcinoma |
5 | Moussian & Schwab, Nies | The model of the fruit fly Drosophila melanogaster as a novel and highly innovative test system for human membrane transporters in anti-cancer drug development |
6 | Ruth, Lukowski & Brauch, Schroth | Genetic variants in KCa channel multiprotein-complexes as predictive factors for breast cancer risk and treatment outcome |
7 | Wehkamp & Stange | Combined histone deacetylase inhibition and E.coli Nissle 1917 treatment as novel therapy in colon carcinoma |
8 | Stevanovic, Bedke & Schwab, Schäffeler | Elucidation of underlying genomic, epigenomic and metabolomic factors contributing to the expression of candidate targets identified by HLA ligandome analysis in ccRCC |
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Z1 | Nürnberg | ICEPHA mouse clinic |
Z2 | Lukowski, Laufer | Administrative and central tasks |