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Graduate Program (2018-2021)

Overview of the Projects

 

 

Project

PIs

Title




1.

B. Moussian / A. Nies

The model of the fruit fly Drosophila melanogaster as a novel and highly innovative test system for human membrane transporters in anti-cancer drug development

 

 

 

2.

S. Laufer / O. Burk

Validation of xenosensing nuclear receptor PXR as a therapeutic target in cancer chemotherapy

 

 

 

3.

R. Lukowski, P. Ruth / W. Schroth, H. Brauch

The role of potassium channels and their gene variants for hormone-dependent breast cancer progression and endocrine treatment outcome

 

 

 

4.

K. Schulze-Osthoff, F. Essmann / M. Schwab, R. Hoppe

Role of the pro-apoptotic BCL-2 protein BOK in breast cancer

 

 

 

5.

L. Danielyan / R. Tremmel

Amyloid beta and its degrading enzyme neprilysin as targets for treatment of liver fibrosis and prevention of hepatocellular carcinoma

 

 

 

6.

S. Beer-Hammer, B. Nürnberg / M. Haag, U. Hofmann

Establishment of Stable lsotope-resolved in vivo Metabolomics as Test System to assess Membrane-associated Drug Targets in Cancer

 

 

 

7.

J. Bedke, V. Stühler / E. Schäffeler, P. Fisel

Intratumor heterogeneity of members of the monocarboxylate transporter (MCT/SLC16) and organic cation transporter (OCT/SLC22) family in clear cell renal cell carcinoma (ccRCC)

 

 

 

8.

K. Schenke-Layland, E.M. Brauchle / T. Mürdter, N. Janssen

FORGI: Fibroblast tumor ORGanoids Immune cell co-culture – a new model to understand membrane-mediated tumor microenvironment interactions

 

 

 

Z1

B. Nürnberg

ICEPHA mouse clinic

Z2

R. Lukowski

Administrative and central tasks