Publications Prof. Dr. P. Ruth
No | Publications |
|---|---|
1. | Flockerzi, V., Mewes, R., Ruth, P. & Hofmann, F. Phosphorylation of purified bovine cardiac sarcolemma and potassium-stimulated calcium uptake. Eur. J. Biochem. 135 (1983), 131-142. |
2. | Ruth, P., Flockerzi, V., von Nettelbladt, E., Oeken, J. & Hofmann, F. Characterization of the binding sites for nimodipine and (-) desmethoxyverapamil in bovine cardiac sarcolemma. Eur. J. Biochem. 150 (1985), 313-322. |
3. | Oeken, J., von Nettelbladt, E., Zimmer, M., Flockerzi, V., Ruth, P. & Hofmann, F. Cardiac sarcoplasmic reticulum contains a low-affinity site for phenylalkylamines. Eur. J. Biochem. 156 (1986), 661-667. |
4. | Ruth, P., Flockerzi, V., Oeken, J. & Hofmann, F. Solubilization of the bovine cardiac sarcolemmal binding sites for calcium channel blockers. Eur. J. Biochem. 155 (1986), 613-620. |
5. | Ruth, P., Röhrkasten, A., Biel, M., Bosse, E., Regulla, S., Meyer, H.E., Flockerzi, V. & Hofmann, F. Primary structure of the ß subunit of the DHP-sensitive calcium channel from skeletal muscle. Science 245 (1989), 1115-1118. |
6. | Hofmann, F., Schneider, T., Röhrkasten, A., Nastainczyk, W., Sieber, M., Ruth, P. & Flockerzi, V. Calcium-Kanäle: Struktur und Funktion des Rezeptors für Calcium-Kanalblocker im Skelettmuskel. Arzneimittelforschung 39 (1989), 164-168. |
7. | Hofmann, F., Flockerzi, V., Nastainzcyk, W., Ruth, P. & Schneider, T. The molecular structure and regulation of muscular calcium channels. Current topics in cellular regulation (1990), pp. 223-239. |
8. | Biel, M., Ruth, P., Bosse, E., Hullin, R., Stühmer, W., Flockerzi, V. & Hofmann, F. Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung. FEBS Lett. 269 (1990), 409-412. |
9. | Bosse, E., Regulla, S., Biel, M., Ruth, P., Meyer, H.E., Flockerzi, V. & Hofmann, F. The cDNA and deduced amino acid sequence of the subunit of the L-type calcium channel from rabbit skeletal muscle. FEBS Lett. 267 (1990), 153-156. |
10. | Kim, S.H., Wei, X., Ruth, P., Perez-Reyes, E., Flockerzi, V., Hofmann, F. & Birnbaumer, L. Studies on the structural requirements for the activity of the skeletal muscle dihydropyridine receptor/slow Ca2+ channel. J. Biol. Chem. 265 (1990), 11858-11863. |
11. | Lacerda, A.E., Kim, H.S., Ruth, P., Perez-Reyes, E., Flockerzi, V., Hofmann, F., Birnbaumer, L. & Brown, A.M. Normalization of current kinetics by interaction between the Ó1 and ß subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature 352 (1991), 527-530. |
12. | Mori, Y., Friedrich, T., Kim, M.S., Mikami, A., Nakai, J., Ruth, P., Bosse, E., Hofmann, F., Flockerzi, V., Furuichi, T., Mikoshiba, K., Imoto, K., Tanabe, T. & Numa, S. Primary structure and functional expression from complementary DNA of a brain calcium channel. Nature 350 (1991), 398-402. |
13. | Ruth, P., Landgraf, W., Keilbach, A., May, B., Egleme, C. & Hofmann, F. The activation of expressed cGMP-dependent protein kinase isozymes IÓ and Iß is determined by the different amino-termini. Eur. J. Biochem. 202 (1991), 1339-1344. |
14. | Landgraf, W., Ruth, P., Keilbach, A., May, B., Welling, A. & Hofmann, F. Cyclic GMP-dependent protein kinase and smooth muscle relaxation. J. Cardiovasc. Pharmacol. 20 (suppl. 1) (1992), S18-S22. |
15. | Welling, A., Bosse, E., Ruth, P., Bottlender, R., Flockerzi, V. & Hofmann, F. Expression and regulation of cardiac and smooth muscle calcium channel. Jap. J. Pharmacol. (1992) 58, Suppl.II: 258P-262P. |
16. | Hofmann, F., Dostmann, W., Keilbach, A., Landgraf, W. & Ruth, P. Structure and physiological role of cGMP-dependent protein kinase. Biochim. Biophys. Acta 1135 (1992), 51-60. |
17. | Keilbach, A., Ruth, P. & Hofmann, F. Detection of cGMP dependent protein kinase by specific antibodies. Eur. J. Biochem. 208 (1992), 467-473. |
18. | Ruth, P., Wang, G.X., Boekhoff, I., May, B., Pfeifer, A., Penner, R., Korth, M., Breer, H. & Hofmann, F. Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of IP3 production. Proc. Natl. Acad. Sci. USA 90 (1993), 2623-2627. |
19. | Feil, R., Bigl, M., Ruth, P. & Hofmann F. Expression of cGMP-dependent protein kinase in Escherichia coli. Mol. Cell. Biochem. 127/128 (1993), 71-80. |
20. | Hofmann, F., Biel, M., Pfeifer, A.& Ruth, P. cGMP increases and decreases cytosolic calcium. J. Muscl. Cell. Motil. (1995) 16, 444-445. |
21. | Pfeifer, A., Nürnberg, B., Kamm, S., Uhde, M., Schultz, G., Ruth, P. & Hofmann, F. Cyclic GMP-dependent protein kinase blocks pertussis toxin-sensitive hormone receptor signaling pathways in CHO cells. J. Biol. Chem. 270 (1995), 9052-9. |
22. | Barger, S.W., Fiscus, R.R., Ruth, P., Hofmann, F. & Mattson, M.P. Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of ß-amyloid precursor. J. Neurochem. 64 (1995), 2087-96. |
23. | Lacinova, L., Welling, A., Bosse, E., Ruth, P., Flockerzi, V. & Hofmann, F. Interaction of Ro 40-5967 and verapamil with the stably expressed Ó1-subunit of the cardiac L-type calcium channel. J. Pharm. Exp. Ther. 274 (1995), 54-63. |
24. | Zhou, X.-B., Ruth, P., Hofmann, F. & Korth, M. Protein phosphatase 2A is essential for the activation of IK(Ca) by cyclic GMP kinase in tracheal smooth muscle and CHO cells. J. Biol. Chem. 271 (1996), 19760-19767. |
25. | Ruth, P., Kamm, S., Nau, U., Pfeifer, A. & Hofmann, F. A cGMP kinase mutant with increased sensitivity to the protein kinase inhibitor peptide PKI(5-24). Biol. Chem. 377 (1996), 513-520. |
26. | Pfeifer, A., Aszodi, A., Seidler, U., Ruth, P., Hofmann, F. & Fässler, R. Intestinal secretory defects and dwarfism in mice lacking GMP-dependent protein kinase II. Science 274 (1996), 2082-2086. |
27. | Suh-Kim, H., Wei, X., Klos, A., Pan, S., Ruth, P., Flockerzi, V., Hofmann, F., Perez-Reyes, E., Birnbaumer, L. Reconstitution of the skeletal muscle dihydropyridine receptor: functional interaction among α1, β, γ and α2δ subunits. Receptors and Channels 4 (1996), 217-225. |
28. | Ruth, P., Pfeifer, A., Kamm, S., Klatt, P., Dostmann, W. R. G., & Hofmann, F. Identification of the amino acid sequences responsible for high affinity activation of cGMP Kinase Iα. J. Biol. Chem. 272 (1997), 10522-10528. |
29. | Zhou, X.-B., Schloßmann, J., Hofmann, F., Ruth, P., & Korth, M. Regulation of stably expressed and native BK channel from human myometrium by cGMP- and cAMP-dependent protein kinase. Pflugers Arch. Eur. J. Physiol. 436 (1998), 725-734. |
30. | Pfeifer, A., Klatt, P., Massberg, S., Ny, L., Sausbier, M., Hirneiß, C., Wang, G.-X., Korth, M., Aszódi, A., Andersson, K.-E., Krombach, F., Mayerhofer, A., Ruth, P., Fässler, R. & Hofmann, F. Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J. 17 (1998), 3045-3051. |
31. | Huber A, Trudrung P, Storr M, Ruth P, Allescher HD. Protein kinase G expression in the small intestine and functional importance for smooth muscle relaxation. Am. J. Physiol. 275 (1998), G629-G637. |
32. | Wagner, C., Pfeifer, A., Ruth, P., Hofmann, F. & Kurtz, A. Role of cGMP kinase II in the control of renin secretion and renin expression. J. Clin. Invest. 102 (1998), 1576-1581. |
33. | Alioua, A., Tanaka, Y., Wallner, M., Hofmann, F., Ruth, P., Meera, P & Toro, L. The large conductance, voltage-dependent and Ca2+-sensitive K+ channel, Hslo, is a target of cGMP-dependent protein kinase phosphorylation. J. Biol. Chem. 273 (1998), 32950-32956. |
34. | Kleppisch, T., Pfeifer, A., Klatt, P., Ruth, P., Montkowski, A., Fässler, R. & Hofmann, F. Long-term potentiation in the hippocampal CA1 region of mice lacking cGMP-dependent protein kinases is normal and susceptible to inhibition of NO synthase. J. Neurosci. 19 (1999), 48-55. |
35. | Pfeifer, A., Ruth, P., Dostmann, W. Sausbier, M., Klatt, P. & Hofmann, F. Structure and function of cGMP-dependent protein kinases. Rev. Physiol. Biochem. Pharmacol. 135 (1999), 105-149. |
36. | Sporbert, A, Mertsch, K, Smolenski, A, Haseloff, RF, Schönfelder, G, Paul, M, Ruth, P, Walter, U, & Blasig IE. Phosphorylation of vasodilator-stimulated phosphoprotein: a consequence of nitric oxide- and cGMP-mediated signal transduction in brain capillary endothelial cells and astrocytes. Mol. Brain Res. 67 (1999), 258-266. |
37. | Massberg, S., Sausbier, M., Klatt, P., Baur, M., Pfeifer, A., Siess, W., Fässler, R., Ruth, P., Krombach, F., Hofmann, F. Increased adhesion and aggregation of platelets lacking cGMP kinase I. J. Exp. Med. 189 (1999), 1255-1263. |
38. | Ruth, P. Cyclic GMP-Dependent Protein Kinases: Understanding in vivo Functions by Gene Targeting. Pharmacol. Ther. 82 (1999), 355-372. |
39. | Klotz T, Bloch W, Zimmermann J, Ruth P, Engelmann U, Addicks K (2000) Soluble guanylate cyclase and cGMP-dependent protein kinase I expression in the human corpus cavernosum. Int J Impot Res 12, 157-164. |
40. | Vaandrager AB, Bot A, Ruth P, Pfeifer A, Hofmann F, de Jonge HR (2000) Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine intestine and colon. Gastroenterology 118, 108-114. |
41. | Huber A, Neuhuber WL, Klugbauer N, Ruth P, Allescher HD (2000) Cysteine rich protein 2, a novel substrate for cGMP kinase I in enteric neurons and intestinal smooth muscle. J Biol Chem 275, 5504-5511. |
42. | Schlossmann J, Ashman K, Ammendola A, Huber A, Neubauer G, Wang GX, Korth M, Wilm M, Hofmann F, Ruth P (2000) Regulation of Ca2+ release in smooth muscle by a signaling complex of IRAG, IP3 receptor and cGMP kinase. Nature 404, 197-201. |
43. | Zhou XB, Wang GX, Ruth P, Hüneke B, Korth M (2000) Activation of BKCa channels by a membrane associated cGMP kinase may contribute to uterine quiescence in pregnant women. Am J Physiol 279, C1751-C1759. |
44. | Sausbier M, Schubert R, Voigt V, Hirneiss C, Pfeifer A, Korth M, Kleppisch T, Ruth P, Hofmann F (2000) Mechanisms of NO/cGMP-dependent vasorelaxation. Circ Res 87, 825-830. |
45. | Zhou XB, Arntz C, Kamm S, Motejlek K, Sausbier U, Wang GX, Ruth P, Korth M (2001) A molecular switch for specific stimulation of the BKCa channel by cGMP and cAMP kinase. J Biol Chem 276, 43239-43245. |
46. | Salmhofer H, Neuhuber WL, Ruth P, Huber A, Russwurm M, Allescher HD (2001) Pivotal role of the interstitial cells of Cajal in the nitric oxide signaling pathway of rat small intestine. Cell Tissue Res 305, 331-340. |
47. | Revermann M, Maronde E, Ruth P, Korf HW (2002) Protein kinase G I immunoreaction is colocalized with arginine-vasopressin immunoreaction in the rat suprachiasmatic nucleus. Neurosci Lett 334, 119-122. |
48. | Tegeder I, Schmidtko A, Niederberger E, Ruth P, Geisslinger G (2002) Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats. Neurosci Lett 332, 146-150. |
49. | Koller A, Schlossmann J, Ashman K, Uttenweiler-Joseph S, Ruth P, Hofmann F (2003) Association of phospholamban with a cGMP kinase signaling complex. Biochem Biophys Res Commun 300, 155-160. |
50. | Schmidtko A, Ruth P, Geisslinger G, Tegeder I (2003) Inhibition of cyclic guanosine 5'-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation. Nitric Oxide 8, 89-94. |
51. | Vaandrager AB, Hogema BM, Edixhoven M, Van Den Burg CM, Bot AG, Klatt P, Ruth P, Hofmann F, Van Damme J, Vandekerckhove J, De Jonge HR (2003) Autophosphorylation of cGMP-dependent protein kinase type II. J Biol Chem 278, 28651-28658. |
52. | Steffens F, Zhou XB, Sausbier U, Sailer C, Motejlek K, Ruth P, Olcese J, Korth M, Wieland T (2003) Melatonin receptor signaling in pregnant and nonpregnant rat uterine myocytes as probed by large conductance Ca2+-activated K+ channel activity. Mol Endocrinol 17, 2103-2115. |
53. | Tegeder I, Del Turco D, Schmidtko A, Sausbier M, Feil R, Hofmann F, Deller T, Ruth P, Geisslinger G (2004) Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I. Proc Natl Acad Sci USA 101, 3253-3257. |
54. | Tian L, Coghill LS, McClafferty H, MacDonald SH, Antoni FA, Ruth P, Knaus HG, Shipston MJ (2004) Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase. Proc Natl Acad Sci USA 101, 11897-11902. |
55. | Sausbier M, Hu H, Arntz C, Feil S, Kamm S, Adelsberger H, Sausbier U, Sailer CA, Feil R, Hofmann F, Korth M, Shipston MJ, Knaus HG, Wolfer DP, Pedroarena CM, Storm JF, Ruth P (2004) Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proc Natl Acad Sci USA 101, 9474-9478. |
56. | Rüttiger L, Sausbier M, Zimmermann U, Winter H, Braig C, Engel J, Knirsch M, Arntz C, Langer P, Hirt B, Müller M, Köpschall I, Pfister M, Münkner S, Rohbock K, Pfaff I, Rüsch A, Ruth P, Knipper M (2004) Deletion of the Ca2+-activated K+ (BK) channel α-subunit but not the BKβ1-subunit leads to progressive hearing loss. Proc Natl Acad Sci USA 101, 12922-12927. |
57. | Schmidtko A, Del Turco D, Coste O, Ehnert C, Niederberger E, Ruth P, Deller T, Geisslinger G, Tegeder I (2005) Essential role of the synaptic vesicle protein synapsin II in formalin-induced hyperalgesia and glutamate release in the spinal cord. Pain 115, 171-178. |
58. | Sausbier M, Arntz C, Bucurenciu I, Feil S, Zhao H, Sausbier U, Kamm S, Zhou XB, Essin K, Sailer CA, Krippeit-Drews P, Feil R, Hofmann F, Knaus HG, Kenyon C, Shipston MJ, Storm JF, Neuhuber W, Korth M, Schubert R, Gollasch M, Ruth P (2005) Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel deficient mice. Circulation 112, 60-68. |
59. | Chen L, Tian L, Macdonald SH, McClafferty H, Hammond MS, Huibant JM, Ruth P, Knaus HG, Shipston MJ (2005) Functionally diverse complement of calcium-activated BK channel α-subunits generated from a single site of splicing. J Biol Chem 280, 33599-33609. |
60. | Sausbier M, Matos JE, Sausbier U, Arntz C, Neuhuber W, Ruth P, Leipziger J (2006) Distal colonic K+ secretion occurs via BK channels. J Am Soc Nephrol 17, 1275-1282. |
61. | Sausbier U, Sausbier M, Sailer C, Arntz C, Knaus H-G, Neuhuber W, Ruth P (2006) Distribution of Ca2+-Activated K+ Channels of the BK-Type in the Mouse Brain. Histochem Cell Biol 125, 725-741. |
62. | Hennige AM, Sartorius T, Tschritter O, Preissl H, Fritsche A, Ruth P, Haring HU (2006) Tissue selectivity of insulin detemir action in vivo. Diabetologia 49, 1274-1282. |
63. | Oliver D, Taberner A, Thurm H, Sausbier M, Arntz C, Ruth P, Fakler B, Liberman MC (2006) The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery. J Neuroscience 26, 6181-6189. |
64. | Sailer CA, Kaufmann WA, Kogler M, Chen L, Sausbier U, Ottersen OP, Ruth P, Shipston MJ and Knaus HG (2006) Immunolocalization of BK channels in hippocampal pyramidal neurons. Eur J Neurosci. 24, 442-454. |
65. | MacDonald SH, Ruth P, Knaus HG and Shipston MJ (2006) Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS. BMC Dev Biol. 6, 37. |
66. | Tian L, Chen L, McClafferty H, Sailer C, Ruth P, Knaus HG, ShipstonMJ (2006) A non-canonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin. FASEB J. 20, 2588-2590. |
67. | Sausbier M, Zhou XB, Beier C, Sausbier U, Wolpers D, Maget S, Martin C, Dietrich A, Ressmeyer AR, Schlossmann J, Hofmann F, Neuhuber W, Gudermann T, Uhlig S, Korth M, Ruth P (2007) Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J. 21, 812-822. |
68. | Essin K, Salanova B, Kettritz R, Sausbier M, Luft FC, Kraus D, Bohn E, Autenrieth IB, Peschel A, Ruth P, Gollasch M (2007) Large-conductance Ca2+-activated K+ channel activity is absent in human and mouse neutrophils and is not required for innate immunity. Am J Physiol Cell Physiol 293, C45-C54. |
69. | Schug N, Braig C, Zimmermann U, Engel J, Winter H, Ruth P, Blin N, Pfister M, Kalbacher H, Knipper M (2006) Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat Eur J Neurosci. 24, 3372-3380. |
70. | Engel J, Braig C, Ruttiger L, Kuhn S, Zimmermann U, Blin N, Sausbier M, Kalbacher H, Munkner S, Rohbock K, Ruth P, Winter H, Knipper M (2006) Two classes of outer hair cells along the tonotopic axis of the cochlea. Neuroscience 143, 837-849. |
71. | Matos JE, Sausbier M, Beranek G, Sausbier U, Ruth P, Leipziger J (2007) Role of cholinergic-activated KCa1.1 (BK), KCa3.1 (SK4) and KV7.1 (KCNQ1) channels in mouse colonic Cl- secretion. Acta Physiol (Oxf) 189, 251-258. |
72. | Rieg T, Vallon V, Sausbier M, Sausbier U, Kaissling B, Ruth P, Osswald H (2007) A role of BK channel in K+ homeostasis and flow-induced renal K+ excretion. Kidney Int 72, 566-573. |
73. | Schmidtko A, Gao W, Sausbier M, Grundei M, Sausbier U, Niederberger E, Scholich K, Huber A, Allescher H-D, Hofmann F, Ruth P, Geisslinger G (2008) Cysteine-rich protein 2, a novel downstream effector of cGMP/cGMP-dependent protein kinase I mediated nociception. J Neurosci 28, 1320-1330. |
74. | Hercule HC, Salanova B, Essin K, Honeck H, Falck JR, Sausbier M, Ruth P, Schunck WH, Luft FC, Gollasch M (2007) The vasodilator 17,18-epoxyeicosatetraenoic acid targets the pore-forming BK alpha channel subunit in rodents. Exp Physiol 92, 1067-1076. |
75. | Brunton PJ, Sausbier M, Wietzorrek G, Sausbier U, Knaus HG, Russell JA, Ruth P, Shipston MJ (2007) Hypothalamic-pituitary-adrenal axis hyporesponsiveness to restraint stress in mice deficient for large-conductance Ca2+- and voltage-activated potassium (BK) channels. Endocrinology 148, 5496-5506. |
76. | Shumilina E, Lam RS, Wölbing F, Matzner N, Zemtsova IM, Sobiesiak M, Mahmud H, Sausbier U, Biedermann T, Ruth P, Sausbier M, Lang F (2008) Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol 180, 8040-8047. |
77. | Zhou XB, Wulfsen I, Lutz S, Utku E, Sausbier U, Ruth P, Wieland T, Korth M (2008) M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gβγ-mediated inhibition of large conductance Ca2+-activated K+ channel activity. J Biol Chem 283, 21036-21044. |
78. | Sørensen MV, Matos JE, Sausbier M, Sausbier U, Ruth P, Praetorius HA, Leipziger J (2008) Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion. J Physiol 586, 4251-4264. |
79. | Schmidtko A, Gao W, König P, Heine S, Motterlini R, Ruth P, Schlossmann J, Koesling D, Niederberger E, Tegeder I, Friebe A, Geisslinger G (2008) cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I. J Neurosci 28, 8568-8576. |
80. | Heidrych P, Zimmermann U, Breß A, Pusch CM, Ruth P, Pfister M, Knipper M, Blin N (2008) Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form. Hum Mol Genet 17, 3814-3821. |
81. | Schmidt S, Richter M, Montag D, Sartorius T, Gawlik V, Hennige AM, Scherneck S, Himmelbauer H, Lutz SZ, Augustin R, Kluge R, Ruth P, Joost HG, Schürmann A (2008) Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice. Am J Physiol Endocrinol Metab 295, E1084-1094. |
82. | Düfer M , Gier B , Wolpers D , Krippeit-Drews P, Ruth P, Drews G (2009) Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells. Diabetes 58, 1835-1843. |
83. | Kaufmann WA, Ferraguti F, Fukazawa Y, Kasugai Y, Shigemoto R, Laake P, Sexton JA, Ruth P, Wietzorrek G, Knaus HG, Storm JF, Ottersen OP (2009) Large-conductance calcium-activated potassium channels in purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains. J Comp Neurol 515, 215-230. |
84. | Winter H, Rüttiger L, Müller M, Kuhn S, Brandt N, Zimmermann U, Hirt B, Bress A, Sausbier M, Conscience A, Flamant F, Tian Y, Zuo J, Pfister M, Ruth P, Löwenheim H, Samarut J, Engel J, Knipper M (2009) Deafness in TRbeta mutants is caused by malformation of the tectorial membrane. J Neurosci 29, 2581-2587. |
85. | Sprossmann F, Pankert P, Sausbier U, Wirth A, Zhou XB, Madlung J, Zhao H, Bucurenciu I, Jakob A, Lamkemeyer T, Neuhuber W, Offermanns S, Shipston MJ, Korth M, Nordheim A, Ruth P, Sausbier M (2009) Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder. FEBS J 276, 1680-1697 |
86. | Heidrych P, Zimmermann U, Kuhn S, Franz C, Engel J, Duncker SV, Hirt B, Pusch CM, Ruth P, Pfister M, Marcotti W, Blin N, Knipper M (2009) Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell. Hum Mol Genet 18, 2779-2790. |
87. | Tian L, Jeffries O, McClafferty H, Molyvdas A, Rowe IC, Saleem F, Chen L, Greaves J, Chamberlain LH, Knaus HG, Ruth P, Shipston MJ (2008) Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels. Proc Natl Acad Sci U S A 105, 21006-21011. |
88. | Essin K, Gollasch M, Rolle S, Weissgerber P, Sausbier M, Bohn E, Autenrieth IB, Ruth P, Luft FC, Nauseef WM, Kettritz R (2009) BK channels in innate immune functions of neutrophils and macrophages. Blood 113, 1326-1331. |
89. | Nickl CK, Raidas SK, Zhao H, Sausbier M, Ruth P, Tegge W, Brayden JE, Dostmann WR (2009) (d)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha. Biochim Biophys Acta, epub ahead of print. |
90. | Cheron G, Sausbier M, Sausbier U, Neuhuber W, Ruth P, Dan B, Servais L (2009) BK channels control cerebellar Purkinje and Golgi cell rhythmicity in vivo. PLoS One 4, e7991, 1-11. |
91. | Hennige AM, Sartorius T, Lutz SZ, Tschritter O, Preissl H, Hopp S, Fritsche A, Rammensee HG, Ruth P, Häring HU (2009) Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity. Diabetologia, epub ahead of print. |
92. | Roth M, Rupp M, Hofmann S, Mittal M, Fuchs B, Sommer N, Parajuli N, Quanz K, Schubert D, Dony E, Schermuly RT, Ghofrani HA, Sausbier U, Rutschmann K, Wilhelm S, Seeger W, Ruth P, Grimminger F, Sausbier M, Weissmann N (2009) Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia. Am J Respir Crit Care Med 180, 353-364. |
